A black and white photo of a woman who's being prepared to have a needle put into her arm with the article title - My Experience Of The Short Synacthen Test (SST) - in the top left corner of the image

My Experience Of The Short Synacthen Test (SST)

This is a blow-by-blow of my short synacthen test experience, so you’ll know what you’ll go through if you have this test, especially if you’re being investigated for hypoglycaemia. I’ll also explain the different elements of what the test looks for.


I got sent a referral letter for my short synacthen test three days before I was to attend the test. However, I had no idea what the test was for. I even tried asking the PALS team for the hospital Trust I was attending for it, and still, I wasn’t told what the test was for.


I knew it had to be something related to one of my many many referrals, I just didn’t know which.



What Is A Short Synacthen Test (SST)?


If it wasn’t for writing this post, I might not have any idea what the test was for. Literally, as I’m writing this article, I’m finding information that might actually explain what this test is for: it’s meant to be a test for adrenal insufficiency.


I have no idea why no one seems to want to tell me what this short synacthen test is for. It’s so annoying that I’ve not had any kind of official statements from anyone about it. It’s bad enough that I’ve already wasted a lot of time and effort chasing up my other hospital appointments over the last couple of months, due to rescheduling problems.


The weirdest part of all this is that I had to fast for the short synacthen test, for 12 hours no less. But that isn’t standard for the short synacthen test. I’m still not 100% sure what that was done for.


This is what I’ve found out about my short synacthen test. Apparently, I’m being tested for Addison’s disease, which would have been nice to know from my doctor. The test is done to check to see if your adrenal glands are producing enough of important hormones. I believe in my case; I was being tested for cortisol.


Cortisol is important to your health because it helps:

  • The body responds to stress.
  • To regulate blood pressure (which could explain my dizziness and light-headedness).
  • To regulate the immune system.
  • To regulate metabolism (might explain why eating can reduce my dizziness and lightheaded symptoms).
  • To salt and water balance (which could also explain a lot of my symptoms).


The test consisted of me getting there by 9 am, although they ended up running late, in part due to the nurse setting everything up. I’ll get to her in a bit. I had to lie down in a reclining chair to have a cannula put in (bearing in mind I still didn’t know what this test was for or what was meant to happen at this point).


I then had a series of blood samples taken, then I was given an injection of synthetic ACTH hormone to stimulate the release of cortisol. I then had more blood samples taken half an hour later, followed by another set of blood samples taken half an hour after that.


Four empty blood collection vials to represent the article title - My Experience Of The Short Synacthen Test (SST)


It appears that the fasting was so my blood could be checked for lipids and/or glucose. Glucose would make sense given that my specialist wanted to test me for hypoglycemia (Making Plans).


My Experience


Now that the technical stuff is out of the way, let me fill you in on my experience, especially with the nurse I mentioned.


I’m not a big fan of needles, but I’ve become a lot more used to needles than I was. Mainly because I’ve had to have so many blood tests and injections over the last few years that my borderline needle phobia has become a lot more manageable.




However, for my short synacthen test, there was a nurse who was setting up the equipment and getting me ready for the test to start. But they didn’t seem to know what they were doing. When I asked about what was meant to happen during the test (because at this point I still didn’t know what was meant to be happening), the nurse didn’t seem to know either. Which really wasn’t reassuring.


This then caused a spike in my nervousness about what was going to happen with these needles. Previously, I’ve had a nurse who was unable to find my vein and just repeatedly stabbed away at me for close to 20 minutes. I was not looking forward to a similar experience: that experience wasn’t even the cause of my hatred of needles.


Thankfully, they changed nurses when it came to doing the test, so my nervousness dropped. My hatred of needles has caused me to miss blood tests and the like. But it’s the anticipation that’s the main problem for me. Once the needles in it don’t bother me anymore. 


Once the cannula was in, the other samples and injections weren’t really a problem, as there was no need for further injections. Leaving me to basically spend the next hour and a half just laying down looking through Facebook on my phone throughout the short synacthen test.


Although, the hormone they injected me with as part of the test (synthetic ACTH), did make me feel incredibly nauseous. But that passed after about five minutes.


The picture is split in two with the top image being of a someone who's about to have a needle put into their arm and the bottom image being of a medical machine for separating and testing blood. The two images are separated by the article title - My Experience Of The Short Synacthen Test (SST)


Luckily, after the first set of blood tests, I was allowed to eat and drink. I stuffed my face with a sandwich and some biscuits a nurse gave me. Plus, some snack chocolate cakes, a pack of crisps, and a milkshake I’d brought with me. I also finally got to take my medication for the day: I can’t dry swallow pills, I struggle to swallow them with water.


Furthermore, if you’d read my previous article, you’d be aware of all the problems I’ve been having keeping track of my appointments. This issue almost caused me to go to the wrong hospital. A last-minute check of my nil-by-mouth instructions the day before the test made me realise I was going to a totally different hospital from what I thought. It was on letter headed paper for the hospital I go to to see my specialist. However, it had a different hospital address, one I hadn’t been to before.


This meant that not only did I have to deal with being nil by mouth whilst I travelled (travelling is bad enough with my balance, light-headedness, and dizziness problems), but I also had to deal with the anxiety of going somewhere I’d never been before. Fun.


I had to check, recheck, recheck, recheck, etc all the buses I was going to catch or could catch to get to the hospital the night before. Then I had to check multiple times before catching the buses in the morning too.


The first bus I got started off ok because it wasn’t that busy when I got on so I could sit down. However, the whole time I’m repeatedly checking the bus stops as we pass them on my app. I also had to repeatedly check the bus numbers for which one I need to catch next whilst I was at the bus stop, all almost as frequently as I breathe.



On the second bus I had to catch, I had to stand up due to how crowded it was. My anxiety was already running high because of how rough I felt for being nil by mouth. Travelling also makes me feel unwell at the best of times, and because I’m stressing about going somewhere new and making a mistake getting there, it all added up to be a rough second leg of my travels.


Once I got to the hospital, I realised just how simple a journey it actually was. It just didn’t feel that way when looking at maps and planning my way there the night before.


If you’re interested in finding out more about any of my other tests, you can find them, hereherehereherehereherehere, and here.


As always, leave your feedback in the comments section below. Also, feel free to share your experiences in dealing with PALS teams, hospital tests, and needles in the comments section below as well. If you want to stay up-to-date with my blog, then sign up for my newsletter below. Alternatively, get push notifications for new articles by clicking the red bell icon in the bottom right corner.


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8 thoughts on “My Experience Of The Short Synacthen Test (SST)

  1. You sound so much like me when it comes to needle phobia. I’ve put off getting serval injections and blood tests just because of how scared I am. By now you would think I was well accustomed to it, but apparently not.

    I wish you all the best in the future and I hope you start to get some answers soon. It seems like so many appointments and tests, but no further forward.

    • I’m not as bad as I use to be with needles, so that’s something at least.

      Hopefully I’ll get some answers on the 26th July when I see my specialist again

  2. Super insightful article, thanks for sharing your experience! I’m pretty sure my cortisol levels are high as well, so this was a timely read for me. Wishing you much success in lowing your stress and increasing relaxation! 🙂

  3. Thank you for sharing your insight. I haven’t heard of this test before. Thank you for sharing your experience.
    Lauren – bournemouthgirl

  4. Reading this makes me realize how long these types of tests and experiences have been a part of your life for, be they for better or worse! I love seeing how your approach to these experiences has changed and evolved since 2019 to 2022, and seeing how planning plays a major role in tackling anxiety. 🙂

    • Yeah, it feels like forever. It’s been like seven years of tests. But now needles don’t really bother me and I’m able to go to my appointments on my own

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